Many diseases, especially cancer, are caused by the abnormal expression of non-coding microRNAs (miRNAs), which regulate gene expression, leading to the development of miRNA-based therapeutics.Synthetic miRNA inhibitors have shown promising efficacy in blocking the activity of aberrant miRNAs that are upregulated in disease-specific pathologies.On
The nutcracker syndrome (NCS) is a rare condition characterized by the entrapment of the left renal vein between the superior mesenteric artery and the aorta.Clinically, it presents with hematuria, flank pain, and symptoms of pelvic Range Hood venous congestion.It is more frequent in females.Conservative treatment is usually proposed children but i
Abstract Background While protein-protein docking is fundamental to our understanding of how proteins interact, scoring protein-protein complex conformations is a critical component of successful docking programs.Without accurate and efficient scoring functions to differentiate between native and non-native binding complexes, Crafts the accuracy of
Hydraulic systems are used in all kinds of industries.Mills, manufacturing, robotics, and Ports require the use of Hydraulic Equipment.Many industries prefer to use hydraulic systems due to their numerous advantages over electrical and mechanical systems.Hence, the growth in demand for hydraulic systems has been increasing over time.Due to its vast
Weed infestation poses a critical challenge to sustainable agriculture, leading to significant crop yield losses and escalating the use of chemical herbicides, which contribute to environmental degradation and health risks.One of the most pressing issues Fencing in weed management is the declining effectiveness of traditional weed control methods,